Key result
The 0 degree orientation of the CarboMedics mitral valve prosthesis resulted in asymmetrical leaflet motion, whereas the 90 degree orientation was associated with symmetrical leaflet motion.
Why the study?
Does the orientation of a bi-leaflet mechanical mitral valve prosthesis affect left ventricular spatial flow patterns and leaflet opening in a porcine model?
Population
18 pigs undergoing mitral valve replacement
Comparison
CarboMedics mitral valve prosthesis implanted in… vs CarboMedics mitral valve prosthesis implanted in…
Design
Preclinical
Follow-up
6 weeks
Authors
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Orientation affects leaflet symmetry in porcine models; leaves open optimal angles for clinical mitral prosthesis implantation.
Does the orientation of a bi-leaflet mechanical mitral valve prosthesis affect left ventricular spatial flow patterns and leaflet opening in a porcine model?
The orientation of a bi-leaflet mechanical mitral valve prosthesis significantly alters left ventricular spatial flow patterns and leaflet kinematics in a porcine model.
Huysmans et al. (1996) studied Mitral valve replacement (animal model) (n=18). CarboMedics mitral valve prosthesis in 0 degree orientation vs. CarboMedics mitral valve prosthesis in 90 degree orientation was evaluated on Left ventricular spatial flow pattern and valve leaflet opening. The 0 degree orientation of the CarboMedics mitral valve prosthesis resulted in asymmetrical leaflet motion, whereas the 90 degree orientation was associated with symmetrical leaflet motion.
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