Key result
Angular positioning of a bileaflet mechanical mitral valve significantly altered left ventricular flow vorticity and shear stress (p<0.001), though no single optimal orientation was identified.
Why the study?
Does the rotational orientation of a bileaflet mechanical mitral valve alter left ventricular flow conditions in an in vitro model?
Population
Elastic model of a beating left ventricle with a 28 mm St. Jude Medical bileaflet mechanical heart valve…
Comparison
Bileaflet mechanical heart valve rotated through… vs Comparisons between the different angular…
Design
Preclinical
Authors
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Mitral MHV orientation may alter LV flow in vitro; optimal angle for patients remains undetermined.
Does the rotational orientation of a bileaflet mechanical mitral valve alter left ventricular flow conditions in an in vitro model?
p-value: p=<0.001
The rotational orientation of a bileaflet mechanical mitral valve significantly alters left ventricular filling hemodynamics in an in vitro model, highlighting the need for 3D flow measurement to determine optimal positioning.
Westerdale et al. (2015) studied Left ventricular flow conditions with mechanical heart valve. Bileaflet mechanical mitral valve rotational orientation (0, 45, and 90 degrees) vs. Comparisons between different angular positions was evaluated on Vorticity and shear stress of left ventricular flow (p=<0.001). Angular positioning of a bileaflet mechanical mitral valve significantly altered left ventricular flow vorticity and shear stress (p<0.001), though no single optimal orientation was identified.
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