Key result
Cryoelectron tomography of a poliovirus-receptor-liposome model revealed that viral RNA transfer across membranes is mediated by long umbilical connectors spanning a ~50 Å gap.
Population
Poliovirus-receptor-liposome model complex produced using Ni-nitrilotriacetic acid lipids and His-tagged…
Design
Preclinical
Authors
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Hypothesis-generating for viral entry mechanisms; extends in vitro models but leaves open physiological relevance.
Cryoelectron tomography reveals that poliovirus RNA transfer across membranes is mediated by long umbilical connectors spanning a ~50 Å gap between the virus and membrane.
Strauss et al. (2013) studied Poliovirus infection. Cryoelectron tomography of a poliovirus-receptor-liposome model revealed that viral RNA transfer across membranes is mediated by long umbilical connectors spanning a ~50 Å gap.
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