Why the study?
Heart failure from intrinsic myocardial damage causes high surgical mortality and poor functional recovery in severe aortic stenosis, whereas heart failure from excessive afterload may resolve after relief of afterload.
Does ventricular afterload predict surgical prognosis in patients with severe aortic stenosis?
Cohort (n=107)
No
Does ventricular afterload predict surgical prognosis in patients with severe aortic stenosis?
This prospective study aims to demonstrate the prognostic value of ventricular afterload on immediate and medium-term surgical outcomes in severe aortic stenosis.
Answers are grounded in this paper and cite their sources.
Higher wall stress may identify lower-risk severe AS subsets; leaves open whether afterload assessment refines surgical risk stratification.
The present study investigates the role of hemodynamic afterload in severe aortic stenosis and its influence on ventricular function. In this disease, heart failure due to intrinsic myocardial damage causes high surgical mortality. When the patient survives the surgical time; functional class deteriorates frequently in medium-term and mortality is also high. On the other hand, when heart failure is due to excessive afterload and normal myocardial structure, reducing excessive afterload is supposed to normalize ventricular function, reduce surgical mortality, and improve long-term survival. In this prospective study we tried to demonstrate the value of ventricular afterload on surgical prognosis in tight aortic valve stenosis in immediate and medium-term..
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Guadalajara-Boo et al. (2022) conducted a cohort in Severe aortic stenosis (n=107). Systolic wall stress (SWS) was evaluated on Mortality from any cause (OR 0.97, 95% CI 0.94-0.99, p=0.039).
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