Key result
Anacardium occidentale bark extract dose-dependently lowers blood pressure in rats with salt-induced hypertension.
Why the study?
Hypertension is a major public health problem requiring multiple treatment approaches, and Anacardium occidentale is widely used locally to treat ailments, motivating an assessment of its antihypertensive effects.
Does methanol extract of Anacardium occidentale bark reduce blood pressure parameters in salt-induced hypertensive rats?
Does methanol extract of Anacardium occidentale bark reduce blood pressure parameters in salt-induced hypertensive rats?
p-value: p=<0.05
Methanol extract of Anacardium occidentale bark demonstrates dose-dependent antihypertensive effects in a rat model of salt-induced hypertension.
May support preclinical exploration of Anacardium occidentale; leaves open translation to human hypertension trials.
Background: Hypertension is an important public health problem that needs multiple treatment approach. Anacardium occidentale Linn. (Anacardiaceae) on the other hand is a plant largely used locally in for treatment of various ailments. The present study therefore assessed the antihypertensive effects of methanol extract of Anacardium occidentale (AO) root back on cardiovascular parameters in high salt fed Wistar rats
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Victor Emojevwe (2021) studied Salt-induced hypertension (n=12). Methanol extract of Anacardium occidentale bark vs. Nifedipine and normal salt diet was evaluated on Reduction in blood pressure parameters (SBP, DBP, MAP) (p=<0.05). Methanol extract of Anacardium occidentale bark significantly reduced systolic, diastolic, and mean arterial blood pressure in a dose-dependent manner in rats with salt-induced hypertension.
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