Why the study?
The study aimed to investigate the association between body mass index and clinical outcomes stratified by age group in patients undergoing hemodialysis.
Does body mass index affect all-cause mortality and cardiovascular events differently across age groups in patients undergoing maintenance hemodialysis?
Population
71,382 patients undergoing maintenance hemodialysis
Comparison
Underweight vs normal vs overweight vs obese BMI categories across age groups
Design
Retrospective population-based cohort study
Key result
Low body mass index was associated with higher all-cause mortality across all age groups compared to normal BMI, while overweight or obese patients had lower or comparable mortality.
Authors
Loading...
May warrant closer monitoring of underweight HD patients across ages; leaves open whether weight gain improves survival.
Cohort (n=71,382)
Does body mass index affect all-cause mortality and cardiovascular events differently across age groups in patients undergoing maintenance hemodialysis?
In patients undergoing maintenance hemodialysis, low BMI is associated with increased mortality across all ages, while the 'obesity paradox' for cardiovascular events is prominent in younger patients but attenuated in those aged ≥75 years.
Kang et al. (2026) conducted a cohort in Maintenance hemodialysis (n=71,382). Body mass index categories (underweight, overweight, obese) vs. Normal body mass index was evaluated on All-cause mortality and cardiovascular events. Low body mass index was associated with higher all-cause mortality across all age groups compared to normal BMI, while overweight or obese patients had lower or comparable mortality.