Key result
Increased QRS width from left bundle branch block is hypothesized to prolong left ventricular systole and shorten diastole, contributing to heart failure development.
Why the study?
There is no generally accepted explanation for the effect of cardiac resynchronization therapy on myocardial contractility.
Does the width of the stimulated QRS complex predict the efficiency of cardiac resynchronization therapy in patients with heart failure and reduced LVEF?
Does the width of the stimulated QRS complex predict the efficiency of cardiac resynchronization therapy in patients with heart failure and reduced LVEF?
The authors hypothesize that increased QRS width from LBBB prolongs energy-consuming systolic processes and shortens diastole, contributing to heart failure and explaining CRT mechanisms.
Answers are grounded in this paper and cite their sources.
May not guide CRT selection yet; leaves open whether stimulated QRS width predicts response in HFrEF.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Kozlov et al. (2019) studied Heart failure with reduced LVEF and delayed intraventricular conduction. Cardiac resynchronization therapy was evaluated. Increased QRS width from left bundle branch block is hypothesized to prolong left ventricular systole and shorten diastole, contributing to heart failure development.
Synapse has enriched 10 related papers. Consider them for comparative context: