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January 1, 2007Health Affairs

The Value Of Antihypertensive Drugs: A Perspective On Medical Innovation

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Why the study?

Does antihypertensive therapy reduce cardiovascular events and mortality in adults aged 40+?

Population

Adults aged 40+ from national survey data

Comparison

Antihypertensive therapy vs No antihypertensive therapy

Design

Other

Key result

Antihypertensive therapy prevented an estimated 86,000 premature cardiovascular deaths in 2001 and generated a benefit-to-cost ratio of at least 6:1.

Authors

DCDavid CutlerGLGenia LongEBErnst R. Berndt

Discussion

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Overview

Antihypertensive strategies remain cost-effective; leaves open need for updated analyses with contemporary regimens and populations.

Study Design

Type

Observational

Structured PICO

Does antihypertensive therapy reduce cardiovascular events and mortality in adults aged 40+?

P
Population
Adults aged 40+ from national survey data
I
Intervention
Antihypertensive therapy
C
Comparator
No antihypertensive therapy (counterfactual scenario)
O
Outcome
Impact on blood pressures, number and cost of heart attacks, strokes, and deathshard clinical

Antihypertensive therapy has provided substantial population-level health and economic benefits, preventing tens of thousands of premature cardiovascular deaths annually.

Cite This Study

Cutler et al. (2007) conducted an observational in Hypertension. Antihypertensive therapy vs. No antihypertensive therapy was evaluated on Impact on blood pressures, cardiovascular events, and deaths. Antihypertensive therapy prevented an estimated 86,000 premature cardiovascular deaths in 2001 and generated a benefit-to-cost ratio of at least 6:1.

synapsesocial.com/papers/6a0b5dd5f6ae10cc607fc73chttps://doi.org/10.1377/hlthaff.26.1.97
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antihypertensive drugs: a perspective on the value of improved blood pressure control in the USA2007 · 6 citations
  2. 2The Benefit, Risks and Cost of Primary Stroke Prevention with Antihypertensive Drugs1994
  3. 3Public health impact of antihypertensive medication use on arterial blood pressure: A pooled cross-sectional analysis of population health surveys2023 · 3 citations
  4. 4Antihypertensive Therapy in Evolution1986 · 39 citations
  5. 5Controlling Hypertension1996 · 46 citations