Key result
Peak exercise mitral systolic velocity below ~8.1 cm/s predicts impaired peak VO2.
Why the study?
Does mitral systolic velocity at peak exercise predict impaired exercise capacity in patients with HFpEF?
Population
50 patients with heart failure with preserved ejection fraction investigated for effort intolerance or dyspnea
Design
Cross-sectional
Authors
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May support risk stratification in HFpEF; leaves open prospective validation before clinical adoption.
Observational (n=50)
Does mitral systolic velocity at peak exercise predict impaired exercise capacity in patients with HFpEF?
Effect estimate: AUC 0.70 (95% CI 0.55-0.84)
p-value: p=0.004
Mitral systolic velocity at peak exercise measured by stress echocardiography can predict impaired exercise capacity and facilitate risk stratification in patients with HFpEF.
Masada et al. (2017) conducted an observational in Heart failure with preserved ejection fraction (HFpEF) (n=50). Mitral systolic velocity (S') at peak exercise was evaluated on Peak VO2 <16.0 mL/kg/min (AUC 0.70, 95% CI 0.55-0.84, p=0.004). Mitral systolic velocity at peak exercise ≤8.13 cm/s predicted impaired exercise capacity (peak VO2 <16.0 mL/kg/min) with an AUC of 0.70 (95% CI 0.55-0.84; P=0.004).
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