Why the study?
Does the Gln27Glu polymorphism in the beta 2-adrenoceptor gene have different associations with obesity in males compared to females?
Population
247 Swedish subjects with BMI ranging from 19.4-53.4 kg/m2, including healthy volunteers, healthy obese…
Comparison
Glu27 allele of the beta 2-adrenoceptor gene vs Gln27 allele / non-obese subjects
Design
Cross-sectional
Authors
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Sex-specific Glu27-obesity associations are hypothesis-generating; prospective studies needed before any clinical consideration.
Does the Gln27Glu polymorphism in the beta 2-adrenoceptor gene have different associations with obesity in males compared to females?
The Gln27Glu polymorphism in the beta 2-adrenoceptor gene exhibits a sexually dimorphic association with obesity, being positively correlated in females and negatively correlated in males.
Hellström et al. (1999) studied this question.
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