Key result
Uncontrolled hyperthyroidism linked to concurrent DVT and PE, suggesting thyroid evaluation for unprovoked VTE.
Why the study?
Most studies focus on deep vein thrombosis risk in hyperthyroidism, but few describe the association between hyperthyroidism and pulmonary embolism.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
Thyroid evaluation should be considered in patients presenting with unprovoked venous thromboembolic events, as hyperthyroidism may induce a hypercoagulable state.
Numerous disorders of coagulation and fibrinolysis have been reported in patients with thyroid diseases, especially with hyperthyroidism. Most articles are focused on deep vein thrombosis risk, however, few of them describe association between hyperthyroidism and pulmonary embolism. We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events.
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Josip Katić (2021) conducted a case report in Hyperthyroidism with concurrent deep vein thrombosis and pulmonary embolism (n=1). Low-molecular weight heparin, vitamin K antagonist, and thiamazole was evaluated. A 43-year-old woman with uncontrolled hyperthyroidism developed concurrent deep vein thrombosis and pulmonary embolism, suggesting thyroid evaluation is warranted in unprovoked venous thromboembolism.
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