Key result
Obesity in Mexican American children was associated with significantly greater total monocyte concentration (P=0.012), MCP-1 (P=0.015), and TNF-α (P=0.002) compared with healthy weight children.
Why the study?
Does obesity alter blood monocyte concentrations, plasma cytokine/chemokine levels, and lipid profiles in Mexican American children compared to healthy weight children?
Population
128 Mexican American children, categorized as healthy weight, overweight, and obese.
Comparison
Obesity and overweight status vs Healthy weight status (zBMI ≤85th percentile)
Design
Cross-sectional
Authors
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May signal early inflammation in obese Mexican American children; hypothesis-generating for longitudinal cardiometabolic risk studies.
Cross-Sectional (n=128)
Does obesity alter blood monocyte concentrations, plasma cytokine/chemokine levels, and lipid profiles in Mexican American children compared to healthy weight children?
p-value: p=0.012
Childhood obesity in Mexican American children is associated with elevated systemic inflammation markers and dyslipidemia, highlighting early immune alterations that may increase future chronic disease risk.
Breslin et al. (2012) conducted a cross-sectional in Obesity (n=128). Obesity (zBMI ≥95th percentile) vs. Healthy weight (zBMI ≤85th percentile) was evaluated on Total monocyte concentration (p=0.012). Obesity in Mexican American children was associated with significantly greater total monocyte concentration (P=0.012), MCP-1 (P=0.015), and TNF-α (P=0.002) compared with healthy weight children.
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