Key result
Diabetes was the strongest predictor of incident heart failure among postmenopausal women with coronary disease (adjusted HR 3.1; 95% CI 2.3-4.2).
Why the study?
What are the risk factors for developing incident heart failure in postmenopausal women with established coronary disease?
Population
2,391 postmenopausal women with established coronary disease and no heart failure at baseline, from 20 US…
Design
Cohort
Follow-up
6.3+/-1.4 years
Authors
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Diabetes may identify high-risk postmenopausal women with CAD for closer HF surveillance; leaves open whether modification alters incidence.
Cohort (n=2,391)
Yes
What are the risk factors for developing incident heart failure in postmenopausal women with established coronary disease?
Effect estimate: HR 3.1 (95% CI 2.3 to 4.2)
Diabetes, particularly when poorly controlled or accompanied by renal insufficiency or obesity, is the strongest predictor of incident heart failure in postmenopausal women with coronary disease.
Bibbins‐Domingo et al. (2004) conducted a cohort in Coronary disease (n=2,391). Diabetes vs. No diabetes was evaluated on Incident heart failure defined by hospital admission or death from heart failure (HR 3.1, 95% CI 2.3 to 4.2). Diabetes was the strongest predictor of incident heart failure among postmenopausal women with coronary disease (adjusted HR 3.1; 95% CI 2.3-4.2).
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