Key result
Quinidine therapy for atrial fibrillation carries unpredictable hazards of sudden death and arterial embolism, though determining its exact causal role in seriously ill patients remains difficult.
Why the study?
What is the incidence and mechanism of sudden death and arterial embolism associated with quinidine therapy in patients with atrial fibrillation?
What is the incidence and mechanism of sudden death and arterial embolism associated with quinidine therapy in patients with atrial fibrillation?
This review highlights the risks of sudden death and arterial embolism associated with quinidine use for atrial fibrillation, emphasizing the challenges in determining causality.
Answers are grounded in this paper and cite their sources.
Supports caution with quinidine in AF due to sudden death and embolism risks; leaves open exact causality in seriously ill patients.
Sudden death and arterial embolism are unpredictable hazards of quinidine therapy for atrial fibrillation that act as deterrents to its most effective use. In this paper an attempt is made to determine the incidence of these accidents as reported in the literature. The mechanism of sudden death is also examined. The difficulty of determining the role of quinidine in producing these accidents in seriously ill patients is clarified.
No takes yet. Share an insight, caveat, or question.
George W. Thomson (1956) conducted a review in Atrial fibrillation. Quinidine was evaluated on Incidence of sudden death and arterial embolism. Quinidine therapy for atrial fibrillation carries unpredictable hazards of sudden death and arterial embolism, though determining its exact causal role in seriously ill patients remains difficult.
Synapse has enriched 10 related papers. Consider them for comparative context: