Key result
Radiofrequency ablation achieves ECG normalization and VT/VF noninducibility in 100% of symptomatic Brugada syndrome patients.
Why the study?
Does radiofrequency ablation of the arrhythmogenic electrophysiological substrate improve ECG pattern normalization and VT/VF noninducibility in symptomatic Brugada syndrome patients with ICDs?
Cohort (n=135)
Does radiofrequency ablation of the arrhythmogenic electrophysiological substrate improve ECG pattern normalization and VT/VF noninducibility in symptomatic Brugada syndrome patients with ICDs?
Epicardial radiofrequency ablation of the arrhythmogenic substrate in symptomatic Brugada syndrome patients effectively normalizes the ECG and prevents VT/VF inducibility.
No takes yet. Share an insight, caveat, or question.
May support ablation for ECG normalization in symptomatic Brugada; leaves open randomized confirmation of clinical outcomes.
Pappone et al. (2017) conducted a cohort in Brugada syndrome (n=135). Radiofrequency ablation of arrhythmogenic electrophysiological substrate was evaluated on Identification and elimination of AES leading to ECG pattern normalization and VT/VF noninducibility. Radiofrequency ablation of the arrhythmogenic electrophysiological substrate led to ECG normalization and VT/VF noninducibility in 100% of symptomatic Brugada syndrome patients.
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