Key result
Overlapping ARVD and Brugada syndrome ECG features suggest a shared pathophysiological basis.
Why the study?
Although arrhythmogenic right ventricular dysplasia and Brugada syndrome are described as distinct entities, research suggests they may not be entirely separate.
Case Report (n=1)
This case report highlights the potential overlap of clinical features between Arrhythmogenic Right Ventricular Dysplasia and Brugada Syndrome in a single patient, suggesting a common pathophysiological basis.
Does not alter syncope evaluation or management; leaves open possible shared pathophysiology between arrhythmogenic right ventricular dysplasia and Brugada syndrome.
Arrhythmogenic right ventricular dysplasia (ARVD) and Brugada syndrome( BS) are associated with an increased risk of sudden cardiac death. Although they are described as two different entities, research suggests that they are not entirely separate. This paper presents a 55 years old male who presented for syncope. Interestingly, his electrocardiogram met the diagnostic criteria for both ARVD and BS. Subsequently, an implantable cardioverter-defibrillator (ICD) was implanted before discharge due to his high risk of sudden cardiac death. This case revealed that ARVD and BS clinical features can coexist in a single patient, and therefore supports the existence of a common pathophysiological basis of both diseases.
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Rabah et al. (2021) conducted a case report in Arrhythmogenic Right Ventricular Dysplasia and Brugada Syndrome Overlap (n=1). Implantable cardioverter-defibrillator (ICD) was evaluated. A 55-year-old male presenting with syncope exhibited electrocardiographic features of both arrhythmogenic right ventricular dysplasia and Brugada syndrome, supporting a shared pathophysiological basis.
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