Key result
Successful catheter ablation of right ventricular outflow tract tachycardia significantly decreased sympathetic nervous activity, reducing the LF/HF ratio from 2.3 to 1.3.
Why the study?
Does catheter ablation alter autonomic nervous activity and reduce ventricular arrhythmias in patients with idiopathic right ventricular outflow tract tachycardia?
Observational (n=8)
No
Does catheter ablation alter autonomic nervous activity and reduce ventricular arrhythmias in patients with idiopathic right ventricular outflow tract tachycardia?
Absolute Event Rate: 1.3% vs 2.3%
p-value: p=<0.05
Successful catheter ablation of RVOT tachycardia decreases sympathetic and increases parasympathetic nervous activity, suggesting that the presence of ventricular tachyarrhythmias elicits sympathetic predominance.
No takes yet. Share an insight, caveat, or question.
May support autonomic effects of ablation in RVOT tachycardia; hypothesis-generating and should not yet change practice.
Mizumaki et al. (1999) conducted an observational in Idiopathic right ventricular outflow tract (RVOT) tachycardia (n=8). Radiofrequency catheter ablation vs. Baseline (pre-ablation) was evaluated on LF/HF ratio at 7-14 days post-ablation (p=<0.05). Successful catheter ablation of right ventricular outflow tract tachycardia significantly decreased sympathetic nervous activity, reducing the LF/HF ratio from 2.3 to 1.3.
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