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January 1, 1987Renal Failure

Ultrafiltration in Diuretic-Resistant Cardiac Failure

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Key result

Ultrafiltration was successfully completed in 12 of 13 patients with diuretic-resistant cardiac failure, removing a mean of 11.8 L of fluid and resulting in sustained symptomatic improvement.

Why the study?

Does ultrafiltration improve symptoms and remove fluid in patients with diuretic-resistant cardiac failure?

Population

n=13 patients with diuretic-resistant cardiac failure and severely distressing peripheral edema.

Design

Case_series

Follow-up

1 week

Authors

ISIan A. SimpsonMonash HealthKSK. SimpsonGlasgow Royal InfirmaryARA P RaeUniversity of Nottingham

Discussion

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Overview

May support ultrafiltration for fluid removal in diuretic-resistant HF; hypothesis-generating and requires randomized confirmation.

Study Design

Type

Observational (n=13)

Structured PICO

Does ultrafiltration improve symptoms and remove fluid in patients with diuretic-resistant cardiac failure?

P
Population
n=13 patients with diuretic-resistant cardiac failure and severely distressing peripheral edema.
I
Intervention
Ultrafiltration
O
Outcome
Symptomatic improvement and volume of fluid removedpatient reported

Ultrafiltration is an effective intervention for fluid removal and symptomatic improvement in patients with diuretic-resistant heart failure.

Cite This Study

Simpson et al. (1987) conducted an observational in Diuretic-resistant cardiac failure (n=13). Ultrafiltration was evaluated on Symptomatic improvement. Ultrafiltration was successfully completed in 12 of 13 patients with diuretic-resistant cardiac failure, removing a mean of 11.8 L of fluid and resulting in sustained symptomatic improvement.

synapsesocial.com/papers/6a0d3d3acae7912d2fa4d830https://doi.org/10.3109/08860228709056325

Topics

Heart failureHFrEF treatment
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ultrafiltration in the management of refractory congestive heart failure.1986 · 70 citations
  2. 2Progress Study of 590 Consecutive Nonsurgical Cases of Coronary Disease Followed 5-9 Years1973 · 314 citations
  3. 3Progress Study of 590 Consecutive Nonsurgical Cases of Coronary Disease Followed 5-9 Years1973 · 544 citations
  4. 4Treatment of Severe Fluid Overload by Ultrafiltration1974 · 199 citations