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April 24, 2021

Safety and efficacy of ultrafiltration on heart failure patients with reduced ejection fraction and diuretic resistance: results from a single-center randomized controlled trial.

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Key result

Ultrafiltration safely improves diuretic sensitivity in diuretic-resistant HFrEF patients.

Why the study?

Does ultrafiltration therapy improve diuretic sensitivity and safety in heart failure patients with reduced ejection fraction and diuretic resistance?

Population

Heart failure patients with reduced ejection fraction and diuretic resistance

Design

RCT, randomized

Discussion

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Member takes

Overview

May support ultrafiltration in diuretic-resistant HFrEF; extends RCT evidence for this population.

Structured PICO

Does ultrafiltration therapy improve diuretic sensitivity and safety in heart failure patients with reduced ejection fraction and diuretic resistance?

P
Population
Heart failure patients with reduced ejection fraction and diuretic resistance
I
Intervention
Ultrafiltration therapy
O
Outcome
Safety and diuretic sensitivity

Ultrafiltration therapy appears safe and improves diuretic sensitivity in HFrEF patients with diuretic resistance.

Cite This Study

A 2021 study studied this question. Ultrafiltration therapy is safe and improves diuretic sensitivity in heart failure patients with reduced ejection fraction and diuretic resistance.

synapsesocial.com/papers/6aa80998eb815e3469da126bhttps://doi.org/10.3760/cma.j.cn112148-20200816-00646
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1[The efficacy and safety of ultrafiltration for patients with heart failure: results from a single-center randomized controlled study].2017 · 5 citations
  2. 2Ultrafiltration in patients with decompensated heart failure and diuretic resistance: an Asian centre’s experience2016 · 9 citations
  3. 3Ultrafiltration in Diuretic-Resistant Cardiac Failure1987 · 17 citations
  4. 4Ultrafiltration is better than diuretic therapy for volume-overloaded acute heart failure patients: a meta-analysis2020 · 21 citations
  5. 5Ultrafiltration for the treatment of diuretic-resistant, recurrent, acute decompensated heart failure: experience in a single center2010 · 9 citations