Key result
Levothyroxine replacement improves LVEF in 2 patients with dilated cardiomyopathy due to severe hypothyroidism.
Why the study?
Does levothyroxine therapy improve left ventricular ejection fraction in patients with dilated cardiomyopathy due to hypothyroidism?
Case Report (n=2)
No
Does levothyroxine therapy improve left ventricular ejection fraction in patients with dilated cardiomyopathy due to hypothyroidism?
Dilated cardiomyopathy due to hypothyroidism is potentially reversible with levothyroxine therapy, though the extent of recovery may depend on the duration of uncontrolled disease.
No takes yet. Share an insight, caveat, or question.
May support thyroid evaluation in new dilated cardiomyopathy; hypothesis-generating and leaves open need for controlled trials.
Roberto et al. (2016) conducted a case report in Dilated cardiomyopathy due to hypothyroidism (n=2). Levothyroxine was evaluated on Improvement in left ventricular ejection fraction (LVEF). Levothyroxine replacement therapy improved left ventricular ejection fraction from 10-15% to 25-45% in two patients with dilated cardiomyopathy due to severe hypothyroidism.
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