Key result
Aortic valve calcification affects 28 to 55% of end-stage renal disease patients, occurring 10 to 20 years earlier than in the general population and progressing rapidly to severe aortic stenosis.
Population
Patients with end-stage renal disease (ESRD) on dialysis
Design
Review
Authors
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ESRD patients may warrant earlier valve surveillance; leaves open optimal intervention timing pending prospective trials.
Aortic valve calcification is highly prevalent and progresses rapidly in ESRD patients due to a combination of mechanical stress, atherosclerosis, and disordered mineral metabolism.
London et al. (2000) conducted a review in End-stage renal disease (ESRD) with aortic valve calcification. Aortic valve calcification affects 28 to 55% of end-stage renal disease patients, occurring 10 to 20 years earlier than in the general population and progressing rapidly to severe aortic stenosis.
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