Key result
Pharmacological targeting of medial elastocalcinosis is proposed as a valuable therapeutic strategy to prevent and reverse age-related large artery stiffening and isolated systolic hypertension.
Design
Review
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No immediate clinical implications; leaves open pharmacological targeting of medial elastocalcinosis as a research priority for isolated systolic hypertension.
Medial elastocalcinosis is proposed as a key therapeutic target for addressing age-related large artery stiffness and isolated systolic hypertension.
Dao et al. (2005) conducted a review in Arteriosclerosis, large artery stiffness, and isolated systolic hypertension. Pharmacological targeting of elastocalcinosis was evaluated. Pharmacological targeting of medial elastocalcinosis is proposed as a valuable therapeutic strategy to prevent and reverse age-related large artery stiffening and isolated systolic hypertension.
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