Key result
Preload recruitable stroke work slope under 40 predicts HF rehospitalization after TEER for FMR.
Why the study?
It was investigated whether the slope of the preload recruitable stroke work relationship could predict rehospitalization in functional mitral regurgitation patients after transcatheter edge-to-edge repair.
Does the slope of the preload recruitable stroke work relationship (Mw) predict heart failure rehospitalization in patients with functional mitral regurgitation undergoing transcatheter mitral edge-to-edge repair?
Cohort (n=24)
No
Does the slope of the preload recruitable stroke work relationship (Mw) predict heart failure rehospitalization in patients with functional mitral regurgitation undergoing transcatheter mitral edge-to-edge repair?
The noninvasive echocardiographic estimation of the slope of the preload recruitable stroke work relationship (Mw) is a superior predictor of heart failure rehospitalization compared to LVEF in patients with functional mitral regurgitation undergoing transcatheter mitral edge-to-edge repair.
BACKGROUND: ; calculated as stroke work / [EDV - k × EDV + {1 - k} × LV wall], where EDV is end-diastolic volume, k is a constant, and LV wall is the volume of the left ventricular wall) could predict rehospitalization in FMR patients after TEER. METHODS AND RESULTS: had a high area under the curve in time-dependent receiver operating characteristic analysis. CONCLUSIONS: is an effective predictor for rehospitalization in FMR patients after TEER.
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Shingu et al. (2024) conducted a cohort in Functional mitral regurgitation (n=24). Transcatheter mitral edge-to-edge repair (TEER) was evaluated on Time until rehospitalization due to heart failure (AUC 0.806, 95% CI 0.63-0.98, p=0.015). In patients with functional mitral regurgitation undergoing transcatheter mitral edge-to-edge repair, a preload recruitable stroke work relationship slope (Mw) <40 erg·cm−3·10^3 significantly predicted heart failure rehospitalization (AUC 0.806).
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