Why the study?
It was unknown whether maximum rate of LV pressure rise (LVdP/dt MAX) or LV Stroke Work (LVSW) is more strongly associated with long-term prognosis after CRT.
Does Left Ventricular Stroke Work (LVSW) outperform LVdP/dt MAX in predicting long-term prognosis in patients undergoing cardiac resynchronization therapy?
Does Left Ventricular Stroke Work (LVSW) outperform LVdP/dt MAX in predicting long-term prognosis in patients undergoing cardiac resynchronization therapy?
Stroke Work is a superior hemodynamic parameter compared to LVdP/dt MAX for predicting long-term mortality and echocardiographic response after cardiac resynchronization therapy.
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LV stroke work may better inform CRT prognosis than dP/dtmax; hypothesis-generating and requires randomized validation before practice change.
Wouters et al. (2023) studied this question.
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