Key result
Among 125 patients with ventricular septal defect, 17 developed congestive heart failure in infancy, of whom 10 died in the first year of life and 7 survived without further complications.
Why the study?
What is the natural history and survival of infants with ventricular septal defect who develop congestive heart failure?
Observational (n=125)
What is the natural history and survival of infants with ventricular septal defect who develop congestive heart failure?
Answers are grounded in this paper and cite their sources.
Indicates substantial early mortality in VSD infants with CHF; leaves open applicability to contemporary management.
Seventeen patients had a history of congestive heart failure in infancy out of a total of 125 cases of ventricular septal defect reviewed. The initial episode of cardiac decompensation occurred in the first 6 months of life. Ten of the patients had evidence of unremitting failure and died in the first year of life, while seven survived infancy. Exacerbations of decompensation after infancy were rare; patients who survived the first year of life did not succumb to complications of the defect in childhood.
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Morgan et al. (1960) conducted an observational in Ventricular septal defect (n=125). Among 125 patients with ventricular septal defect, 17 developed congestive heart failure in infancy, of whom 10 died in the first year of life and 7 survived without further complications.
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