Key result
Higher baseline SDI links to ~9% lower risk of death, transplant, or LVAD after CRT.
Why the study?
Does the systolic dyssynchrony index (SDI) measured by 3DE predict long-term outcomes in patients undergoing cardiac resynchronization therapy?
Cohort (n=414)
Does the systolic dyssynchrony index (SDI) measured by 3DE predict long-term outcomes in patients undergoing cardiac resynchronization therapy?
Effect estimate: HR 0.914
p-value: p=0.003
Baseline systolic dyssynchrony index assessed by 3D echocardiography is an independent predictor of long-term survival and freedom from heart replacement therapy after CRT implantation.
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SDI by 3DE may aid post-CRT prognostication; leaves open whether it improves selection or outcomes.
Höke et al. (2018) conducted a cohort in Patients undergoing cardiac resynchronization therapy (n=414). Systolic dyssynchrony index (SDI) assessment was evaluated on Combined all-cause mortality, heart transplantation, and LV assist device implantation (HR 0.914, p=0.003). Baseline systolic dyssynchrony index (SDI) assessed by 3D echocardiography was independently associated with the combined endpoint of mortality, heart transplant, or LVAD after CRT (HR 0.914, P=0.003).
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