Key result
Adeno-associated viral gene therapy approaches show promise for treating arthritis and other immune-related inflammatory disorders, though significant developmental hurdles remain.
This review highlights the preclinical progress and clinical hurdles of adeno-associated viral gene therapy, particularly for rheumatoid arthritis.
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AAV gene therapy remains investigational for arthritis; leaves open the need for clinical trials to address translational hurdles.
Aalbers et al. (2011) conducted a review in Arthritis and immune-related inflammatory disorders. Adeno-associated viral gene therapy was evaluated. Adeno-associated viral gene therapy approaches show promise for treating arthritis and other immune-related inflammatory disorders, though significant developmental hurdles remain.
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