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May 3, 2005Hypertension

Advancing age was independently associated with increased aortic input impedance, showing a 37% increase in the frequency of the minimum modulus between the third and seventh decade (P<0.0001).

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Population

71 healthy men and women aged 20 to 69 years

Design

Cross-sectional

Key result

Advancing age was independently associated with increased aortic input impedance, showing a 37% increase in the frequency of the minimum modulus between the third and seventh decade (P<0.0001).

Authors

LMLuciano MazzaroSAStephen J. AlmasiRSRobin Shandas

Discussion

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Overview

Age-associated aortic impedance rise may contribute to cardiovascular risk; hypothesis-generating, requiring prospective studies before any clinical application.

Study Design

Type

Cross-Sectional (n=71)

Structured PICO

P
Population
71 healthy men and women aged 20 to 69 years
O
Outcome
Aortic input impedance (frequency of the minimum modulus)surrogate

Main Result

Effect estimate: r=0.48

p-value: p=<0.0001

Aortic input impedance increases with advancing age in healthy individuals, which may be a mechanism for age-related cardiovascular risk.

Cite This Study

Mazzaro et al. (2005) conducted a cross-sectional in Healthy (n=71). Advancing age was evaluated on Frequency of the minimum modulus of aortic input impedance (r=0.48, p=<0.0001). Advancing age was independently associated with increased aortic input impedance, showing a 37% increase in the frequency of the minimum modulus between the third and seventh decade (P<0.0001).

synapsesocial.com/papers/6a0db3ac6e03bc61cb09e233https://doi.org/10.1161/01.hyp.0000164579.73656.c4
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