Key result
Measurement of pressure-flow relationships showed femoral vascular resistance decreased to 75% of control during reactive hyperemia and increased to 232% following norepinephrine administration.
Why the study?
What are the pressure-flow relationships and hydraulic input impedance characteristics in the ascending aorta and femoral artery of humans under baseline and stimulated conditions?
Population
14 human subjects (3 for ascending aorta measurements, 11 for common femoral artery measurements)
Comparison
Measurement of instantaneous blood flow and… vs Baseline/control values
Design
Other
Authors
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Defines human femoral reactivity metrics; extends foundational physiology but leaves open clinical translation.
Observational (n=14)
What are the pressure-flow relationships and hydraulic input impedance characteristics in the ascending aorta and femoral artery of humans under baseline and stimulated conditions?
This early physiological study characterizes the hydraulic input impedance and pressure-flow relationships in the human aorta and femoral artery, demonstrating significant resistance changes in response to hyperemia and norepinephrine.
Patel et al. (1965) reported an observational. Reactive hyperemia and norepinephrine administration vs. Control value was evaluated on Hydraulic input impedance and vascular resistance. Measurement of pressure-flow relationships showed femoral vascular resistance decreased to 75% of control during reactive hyperemia and increased to 232% following norepinephrine administration.
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