Key Points
- The study aims to examine how the shape of the ascending aortic pressure wave form correlates with aortic input impedance in individuals without heart disease.
- 18 patients underwent elective cardiac catheterization to assess aortic pressure and flow dynamics.
- A multisensor catheter simultaneously recorded ascending aortic flow velocity and pressure for impedance analysis.
- Input impedance was calculated using 10 harmonics of pressure and flow, averaged over 15 beats during steady state.
- Peripheral resistance was measured at 1137 ± 39 dyn-sec-cm (4 SEM).
- Characteristic impedance was found to be 474 dyn-sec-cm; pulse-wave velocity averaged 6.68 ± 0.32 m-sec.
- Patients were categorized into three groups based on systolic pressure dynamics, influencing impedance behaviors.
Structured PICO
PPopulation18 patients who underwent elective cardiac catheterization but in whom no heart disease was found.
IInterventionSimultaneous recording of ascending aortic flow velocity and pressure using a multisensor catheter to calculate aortic input impedance.
OOutcomeRelationship between the shape of the ascending aortic pressure wave form and aortic input impedance.surrogate
In patients with normal hearts, aortic input impedance patterns correlate with the shape of the ascending aortic pressure waveform, specifically the relationship between early and late systolic pressures.