Clinical practice guidelines report significant regional disparities in lifetime prevalence of male infertility, highlighting novel approaches to manage male factors.
The World Health Organization (WHO) estimates that one in six individuals worldwide will experience infertility at some point in their lives, regardless of geographic location or available resources.Data suggests that the estimated lifetime prevalence of infertil-ity varies significantly by region, ranging from as high as 23.2% in the Western Pacific to as low as 10.7% in the Eastern Mediterranean [1].Male factors contribute to 30% to 50% of infertility cases [2,3].To address severe male infertility, intracyto-
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Pescatori et al. (2025) studied this question.
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