Key result
Intensive BP thresholds linked to ~67% lower control rates versus standard targets in community patients.
Why the study?
The study aimed to describe the blood pressure control rate and 10-year ASCVD risk estimation among community hypertensive patients.
What are the blood pressure control rates and 10-year ASCVD risk estimates among Chinese community hypertensive patients using intensive versus standard thresholds?
Cross-Sectional (n=196,803)
What are the blood pressure control rates and 10-year ASCVD risk estimates among Chinese community hypertensive patients using intensive versus standard thresholds?
Half of Chinese community hypertensive patients do not achieve standard BP control, and intensive thresholds further reduce control rates, highlighting a high residual ASCVD risk.
The present study aimed to describe the blood pressure (BP) control rate and 10-years arteriosclerotic cardiovascular disease (ASCVD) risk estimation among community hypertensive patients. A total of 196,803 subjects were enrolled. The control rates calculated as the intensive (SBP < 130 mmHg and DBP < 80 mmHg) and standard (SBP < 140 mmHg and DBP < 90 mmHg) threshold. Multivariable logistic analysis was employed to assess the associations between cardiovascular factors and BP control. Sensitivity, specificity and Youden's index were used to identify the ability of high risk of ASCVD estimation by different thresholds. The control rate was 16.34% and 50.25% by the intensive and standard threshold, respectively. Besides regular medication, the risk factors for BP control included older age, male, unhealthy lifestyle, obesity, dyslipidemia and abnormal FPG. 25.08% of subjects had high risk of 10-years ASCVD estimation. The sensitivity, specificity and Youden's index of intensive threshold was 84.37%, 16.15% and 0.51%, and were significantly different from 50.55%, 50.42% and 0.98% of the standard threshold, respectively. Half of community hypertensive patients did not control BP, and nearly a quarter have high risk of 10-years ASCVD risk estimation. The intensive threshold resulted in a one-third reduction in the control rate compared to the standard threshold. No matter which threshold was used, a single BP control status seemed not a suitable indicator for identification of high risk of 10-years ASCVD risk estimation.
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Liu et al. (2021) conducted a cross-sectional in Hypertension (n=196,803). Intensive BP threshold (SBP < 130 and DBP < 80 mmHg) vs. Standard BP threshold (SBP < 140 and DBP < 90 mmHg) was evaluated on Blood pressure control rate. The intensive BP threshold resulted in a control rate of 16.34% compared to 50.25% with the standard threshold among Chinese community hypertensive patients.
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