Key result
Female TAVR patients face more procedural complications but show better medium-term survival than males.
Why the study?
Are there sex-related differences in the physiology, risk, and outcomes of transcatheter aortic valve replacement between females and males?
Are there sex-related differences in the physiology, risk, and outcomes of transcatheter aortic valve replacement between females and males?
This review highlights that while females undergoing TAVR face higher procedural complication rates, they experience better medium-term survival compared to males.
Answers are grounded in this paper and cite their sources.
Supports sex-specific TAVR risk discussions; leaves open need for prospective validation before practice change.
Transcatheter aortic valve replacement (TAVR) is a less-invasive alternative to surgical aortic valve replacement (SAVR) for the management of symptomatic severe aortic stenosis in patients with inoperable, high, or intermediate surgical risk. Females undergoing TAVR exhibit distinct physiology and baseline characteristics from their male counterparts. Although rates of procedural complications are higher, medium-term survival appears better for females than males. These sex-based differences are discussed in depth in this review of TAVR in the female population.
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Chen et al. (2016) conducted a review in Symptomatic severe aortic stenosis. Transcatheter aortic valve replacement (TAVR) vs. Males undergoing TAVR was evaluated. Females undergoing TAVR exhibit higher rates of procedural complications but better medium-term survival compared to their male counterparts.
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