Key result
Depressive symptoms were prospectively associated with higher glucose levels 11 years later in women (β = 0.07, p = 0.023) but not in men, with no evidence of a reverse association.
Why the study?
Is there a bidirectional association between depressive symptoms and glucose levels in women and men?
Cohort (n=2,534)
Is there a bidirectional association between depressive symptoms and glucose levels in women and men?
Effect estimate: β = 0.07
p-value: p=0.023
Depressive symptoms predict future fasting glucose levels in women but not men, without evidence of a bidirectional relationship or mediation by lifestyle factors.
Depressive symptoms may flag future glucose issues in women; leaves open bidirectionality, mechanisms, and clinical utility pending replication.
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Wesołowska et al. (2018) conducted a cohort in Depressive symptoms and glucose levels (n=2,534). Depressive symptoms was evaluated on Glucose levels in 2012 (β = 0.07, p=0.023). Depressive symptoms were prospectively associated with higher glucose levels 11 years later in women (β = 0.07, p = 0.023) but not in men, with no evidence of a reverse association.
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