Key result
Moderate or severe depressive symptoms at baseline were associated with a 2.3 times higher risk of developing type 2 diabetes over 8 years compared to no depression (HR 2.3; P<0.05).
Why the study?
Do moderate or severe depressive symptoms increase the incidence of type 2 diabetes in Japanese men?
Population
2,764 male employees of an electrical company in Japan
Comparison
Moderate or severe levels of depressive symptoms vs Not depressed
Design
Cohort
Follow-up
8 years
Authors
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Supports depression screening to flag diabetes risk in Japanese men; leaves open whether treatment reduces incidence.
Cohort (n=2,764)
Do moderate or severe depressive symptoms increase the incidence of type 2 diabetes in Japanese men?
Effect estimate: HR 2.3
p-value: p=< 0.05
Moderate or severe depressive symptoms are associated with a significantly increased risk of developing type 2 diabetes in Japanese men.
Kawakami et al. (1999) conducted a cohort in Type 2 diabetes (n=2,764). Moderate or severe depressive symptoms (≥48 on SDS) vs. Not depressed (≤39 on SDS) was evaluated on Incidence of type 2 diabetes (HR 2.3, p=< 0.05). Moderate or severe depressive symptoms at baseline were associated with a 2.3 times higher risk of developing type 2 diabetes over 8 years compared to no depression (HR 2.3; P<0.05).
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