June 1, 1996Arteriosclerosis Thrombosis and Vascular Biology
Coronary Artery Disease in IDDM
Key result
In IDDM, 4-year CAD incidence was similar between sexes, but risk factors differed: renal disease was stronger in men, while physical activity and waist-to-hip ratio were more important in women.
Population
Participants in the Pittsburgh Epidemiology of Diabetes Complications Study recruited from the Children's…
Design
Cohort
Follow-up
4 years
Authors
Discussion
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Implication
Sex differences in IDDM CAD predictors are hypothesis-generating; prospective studies needed before sex-specific strategies.
Study Design
Type
Cohort
Multicenter
No
Structured PICO
P
Population
Participants in the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study recruited from the Children's Hospital of Pittsburgh IDDM registry, diagnosed with insulin-dependent diabetes mellitus (IDDM) between 1950 and 1980.
O
Outcome
Incidence of new coronary artery disease (CAD) events at 4 years of follow-uphard clinical
In patients with IDDM, the 4-year incidence of CAD is similar between sexes, but the predictive risk factors differ significantly, suggesting the need for sex-specific preventive approaches.
Cite This Study
Lloyd et al. (1996) conducted a cohort in Insulin-dependent diabetes mellitus (IDDM). Risk factors for CAD by gender was evaluated on Incidence of new CAD events. In IDDM, 4-year CAD incidence was similar between sexes, but risk factors differed: renal disease was stronger in men, while physical activity and waist-to-hip ratio were more important in women.