Key result
Concomitant Maze IV for AF yields ~69% freedom from atrial arrhythmias at 5 years.
Why the study?
The Maze IV procedure is considered the gold standard for surgical ablation of AF, but long-term follow-up results are scarce.
Does the concomitant Maze IV procedure improve long-term freedom from atrial arrhythmias in patients with atrial fibrillation undergoing cardiac surgery?
Cohort (n=117)
No
Does the concomitant Maze IV procedure improve long-term freedom from atrial arrhythmias in patients with atrial fibrillation undergoing cardiac surgery?
The concomitant Maze IV procedure provides durable long-term rhythm control, with 69% of patients remaining free of atrial fibrillation at 5 years.
May support concomitant Maze IV for durable AF control during cardiac surgery; leaves open randomized confirmation of benefit.
Objective The Maze IV (M-IV) procedure is regarded as the golden standard in treatment for surgical ablation of atrial fibrillation (AF); however, long-term follow-up results are scarce. We present our institutional 10-year experience.Methods We collected data of 117 consecutive patients who have undergone a concomitant M-IV procedure between April 2006 and April 2016. Primary endpoints are freedom of atrial arrhythmias and freedom of atrial arrhythmias off antiarrhythmic drugs (AAD).Results Forty-seven patients (40.2%) had paroxysmal AF. Two-thirds of the procedures included mitral valve surgery. The average follow-up time per patient was 3.8 years (SD 2.8). Freedom of AF at 1 year was 79%, at 5 years freedom of AF was 69% and freedom of AF off AAD was 56%. Predictors of AF recurrence in multivariate analysis were age, preoperative pacemakers, redo cardiac surgery and in-hospital AF. Preoperative PVI ablation was found to be a protective factor.Conclusions The long-term outcomes of the M-IV procedure are good and remain stable over the years. Results could be improved if follow-up were to be intensified and recurrences dealt with aggressively. Key question: How many patients are free from AF in a 10-year period after concomitant M-IV surgical ablation? Key findings: In the long term around 70% of patients are free of AF with an increasing need for anti-arrhythmic drugs. Take home message: Early to midterm freedom from AF after concomitant M-IV procedure is high and remains stable after 3 years.
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François et al. (2021) conducted a cohort in Atrial fibrillation (n=117). Concomitant Maze IV (M-IV) procedure was evaluated on Freedom of atrial arrhythmias and freedom of atrial arrhythmias off antiarrhythmic drugs (AAD). The concomitant Maze IV procedure for atrial fibrillation resulted in 69% of patients being free of atrial arrhythmias at 5 years, with 56% free of arrhythmias off antiarrhythmic drugs.
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