Key result
Organ-specific cardiac autoantibodies in symptom-free relatives are predictive markers of progression to dilated cardiomyopathy, with or without abnormal echocardiographic findings.
Why the study?
Are circulating cardiac autoantibodies predictive markers of progression to DCM in symptom-free relatives of patients with DCM/myocarditis?
Population
Patients with dilated cardiomyopathy (DCM) and myocarditis, and their symptom-free relatives
Design
Review
Authors
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Cardiac autoantibodies may flag DCM risk in asymptomatic relatives; leaves open prospective validation before screening adoption.
Are circulating cardiac autoantibodies predictive markers of progression to DCM in symptom-free relatives of patients with DCM/myocarditis?
Circulating cardiac autoantibodies may serve as predictive markers for the progression to dilated cardiomyopathy in symptom-free relatives of affected patients.
Caforio et al. (2002) conducted a review in Dilated cardiomyopathy and myocarditis. Organ-specific cardiac autoantibodies in symptom-free relatives are predictive markers of progression to dilated cardiomyopathy, with or without abnormal echocardiographic findings.
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