Key result
Obstructive sleep apnea independently predicted recurrent atrial fibrillation after radiofrequency catheter ablation (OR 3.04; 95% CI 1.11-8.32; P=0.03), whereas obesity did not affect outcomes.
Why the study?
Does obstructive sleep apnea or body mass index predict recurrent atrial fibrillation after radiofrequency catheter ablation in patients with atrial fibrillation?
Cohort (n=324)
Does obstructive sleep apnea or body mass index predict recurrent atrial fibrillation after radiofrequency catheter ablation in patients with atrial fibrillation?
Effect estimate: OR 3.04 (95% CI 1.11-8.32)
Absolute Event Rate: 41% vs 63%
p-value: p=0.03
Obstructive sleep apnea, but not obesity, is an independent predictor of recurrent atrial fibrillation following radiofrequency catheter ablation.
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OSA may warrant pre-ablation evaluation; hypothesis-generating for whether treatment improves outcomes in trials.
Jongnarangsin et al. (2008) conducted a cohort in Atrial fibrillation (n=324). Obstructive sleep apnea vs. No obstructive sleep apnea was evaluated on Freedom from recurrent AF without antiarrhythmic drug therapy (OR 3.04, 95% CI 1.11-8.32, p=0.03). Obstructive sleep apnea independently predicted recurrent atrial fibrillation after radiofrequency catheter ablation (OR 3.04; 95% CI 1.11-8.32; P=0.03), whereas obesity did not affect outcomes.
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