Key result
A mathematical model demonstrated that an anastomotic angle of at least 30° and perfect axis alignment minimizes flow disturbances and shear stress in coronary artery bypass grafts.
Why the study?
Coronary graft durability and patency can be negatively affected by technical factors such as the inclination angle and alignment of the coronary anastomosis, which may induce graft thrombosis.
Does the inclination angle and alignment of coronary anastomosis affect flow turbulence in a mathematical model?
Does the inclination angle and alignment of coronary anastomosis affect flow turbulence in a mathematical model?
Mathematical modeling indicates that an anastomotic angle of at least 30° and perfect axial alignment minimize flow turbulence, potentially reducing early graft occlusion in CABG.
Does not support changing CABG anastomosis technique; leaves open in vivo validation of flow optimization.
The durability and patency of a coronary graft can be negatively affected by technical factors that induce thrombosis of the graft and poor prognosis of patients undergoing coronary artery bypass grafting. Technical factors include the inclination angle of the coronary anastomosis and the alignment between the main vessel and the inserted vessel as graft. We have studied a mathematical model aimed to assess the best angulation of the anastomosis and the influence of a correct alignment in order to prevent the risk of early graft occlusion. From data obtained from the mathematical model, in our opinion an inclination of the anastomotic angle of at least 30° seems to be a right choice when performing a coronary artery bypass graft. In addition, the incision of the coronary vessel should be done perfectly on the same axis as that performed on the graft, since even a deviation of the axis of the anastomosis of only 10° can create turbulence of the flow in the anastomosis site, which is accentuated when the deviation reaches 20°.
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Ruvolo et al. (2019) studied Coronary artery bypass grafting. Anastomosis angle of 30° vs. Anastomosis angle of 15° or 45° was evaluated on Perimeter of the graft anastomosis and flow disturbances. A mathematical model demonstrated that an anastomotic angle of at least 30° and perfect axis alignment minimizes flow disturbances and shear stress in coronary artery bypass grafts.
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