Key result
Phase 2 reentry from repolarization abnormalities underlies VF across all J wave syndromes.
This review clarifies the historical evolution and current controversies regarding the definition and arrhythmogenic mechanisms of J wave syndromes, distinguishing between repolarization and depolarization abnormalities.
Clinical management of J wave syndromes unchanged; leaves open unifying phase 2 reentry mechanism pending definitional resolution.
The concept of J wave syndromes was first proposed in 2004 by Yan et al for a spectrum of electrocardiographic (ECG) manifestations of prominent J waves that are associated with a potential to predispose affected individuals to ventricular fibrillation (VF). Although the concept of J wave syndromes is widely used and accepted, there has been tremendous debate over the definition of J wave, its ionic and cellular basis and arrhythmogenic mechanism. In this review article, we attempted to discuss the history from which the concept of J wave syndromes (JWS) is evolved and current controversies in JWS.
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Liu et al. (2016) conducted a review in J Wave Syndromes. Phase 2 reentry from a repolarization abnormality serves as the common mechanism underlying ventricular fibrillation in all J wave syndromes, despite ongoing controversies regarding their definitions.
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