Why the study?
Do patients with diabetes mellitus presenting with acute coronary syndromes have more vulnerable coronary plaque characteristics compared to those without diabetes?
Population
322 patients with acute coronary syndromes who underwent preintervention optical coherence tomography…
Comparison
Diabetes mellitus (DM) vs No diabetes mellitus
Design
Cross-sectional
Key result
Patients with diabetes mellitus presenting with acute coronary syndromes had a higher prevalence of lipid-rich plaque in culprit lesions compared to those without diabetes (58.9% vs 44.9%, P=0.030).
Authors
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Suggests greater plaque vulnerability in diabetic ACS; hypothesis-generating and should not yet change practice.
Observational (n=322)
Do patients with diabetes mellitus presenting with acute coronary syndromes have more vulnerable coronary plaque characteristics compared to those without diabetes?
Absolute Event Rate: 58.9% vs 44.9%
p-value: p=0.030
Patients with diabetes presenting with acute coronary syndromes exhibit more vulnerable plaque features in both culprit and nonculprit lesions on optical coherence tomography, indicating greater panvascular instability.
Sugiyama et al. (2018) conducted an observational in Acute coronary syndromes (n=322). Diabetes Mellitus vs. No Diabetes Mellitus was evaluated on Prevalence of lipid-rich plaque in the culprit lesion (p=0.030). Patients with diabetes mellitus presenting with acute coronary syndromes had a higher prevalence of lipid-rich plaque in culprit lesions compared to those without diabetes (58.9% vs 44.9%, P=0.030).