Key result
Early-onset prosthetic valve endocarditis is linked to ~77% higher hospital mortality than late-onset cases.
Why the study?
The study was conducted to evaluate valve-related factors and the incidence of prosthetic valve endocarditis based on institutional experience.
Are valve-related factors associated with the incidence of prosthetic valve endocarditis?
Observational (n=36)
Are valve-related factors associated with the incidence of prosthetic valve endocarditis?
Valve type, size, and position do not influence prosthetic valve endocarditis incidence, but mitral valve repair has a lower risk than replacement.
Answers are grounded in this paper and cite their sources.
Early-onset prosthetic valve endocarditis may warrant closer post-operative monitoring; this cohort study leaves open causal links to valve characteristics.
AIM: The aim of the study was to present our experience and evaluate the valve-related factors and the incidence of prosthetic valve endocarditis. MATERIAL AND METHODS: This is a retrospective study. Between 2010 and 2018, 36 patients were re-operated on due to prosthetic valve endocarditis The valve-related factors (type, size and position of the prosthetic valve) were analysed. RESULTS: Thirty-six patients had prosthetic valve endocarditis. The overall hospital mortality was 16.67%. Early vs. late onset prosthetic valve endocarditis mortality was 23.08% vs. 13.04% respectively. The type, size or position of the prosthesis was not associated with prosthetic valve endocarditis. There was a statistically significant difference between occurrence of prosthetic infection between mitral repair and replacement both in mechanical and biological valve groups. The most common infective agent in the early onset group was Staphylococcus aureus, whereas in the late onset group it was Enterococcus faecalis. Out of 13 patients with early prosthetic valve endocarditis, 11 had infection in the perioperative period around primary operation. CONCLUSIONS: Based on our experience, prosthetic valve endocarditis has a high mortality. Early onset prosthetic valve endocarditis is less common but has higher mortality compared to the late onset. Mitral valve repair was less prone to develop prosthetic valve endocarditis, and valve-related factors (type and size of the valve, valve position) did not have any influence on the incidence of prosthetic valve endocarditis.
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Bezák et al. (2020) conducted an observational in Prosthetic valve endocarditis (n=36). Valve-related factors (type, size, position) was evaluated on Hospital mortality. Prosthetic valve endocarditis had an overall hospital mortality of 16.67%, with early-onset cases having higher mortality than late-onset cases.
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