Key result
Upgrading to LBBP linked to ~58 ms shorter QRS duration after chronic RVP in HF.
Why the study?
Chronic RV pacing is linked to increased heart failure and mortality, while LBB pacing provides near-physiological activation, but the effects of upgrading to LBB pacing in this setting required investigation.
Does upgrading to left bundle branch pacing improve cardiac function and symptoms in heart failure patients after chronic right ventricular pacing?
Population
27 patients with heart failure after chronic RV pacing
Comparison
Upgrading to LBB pacing evaluated before and after upgrade
Design
Consecutive observational cohort study
Follow-up
Mean 10.4 ± 6.1 months
Authors
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LBB upgrade may narrow QRS after chronic RV pacing in HF; leaves open effects on function, symptoms, and need for RCTs.
Observational (n=27)
Does upgrading to left bundle branch pacing improve cardiac function and symptoms in heart failure patients after chronic right ventricular pacing?
Absolute Event Rate: 116.6% vs 174.1%
p-value: p=< .0001
Upgrading to left bundle branch pacing in patients with heart failure after chronic right ventricular pacing significantly shortens QRS duration and improves LVEF and symptoms.
Qian et al. (2020) conducted an observational in Heart failure after chronic right ventricular pacing (n=27). Left bundle branch pacing upgrade vs. Baseline (chronic right ventricular pacing) was evaluated on Paced QRS duration (p=< .0001). Upgrading to left bundle branch pacing in heart failure patients after chronic right ventricular pacing significantly shortened paced QRS duration from 174.1 to 116.6 milliseconds (p < .0001).
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