Why the study?
Hypertrophic cardiomyopathy presenting with high-degree atrioventricular block is rarely reported in China.
Highlights a rare presentation of hypertrophic cardiomyopathy with progressive complete heart block driven by dual genetic variants, emphasizing the importance of family screening and pacemaker implantation to prevent sudden cardiac death.
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Supports consideration in rare HCM with AV block; hypothesis-generating and should not yet change practice.
Gu et al. (2025) studied this question.
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