Key result
Higher total cholesterol, LDL-C, and triglycerides are linked to more prevalent and severe hypertensive retinopathy.
Why the study?
The study was conducted to evaluate the association between components of the lipid profile and hypertensive retinopathy in patients with essential hypertension.
Cross-Sectional (n=80)
No
In patients with essential hypertension, elevated total cholesterol, LDL-cholesterol, triglycerides, and LDL:HDL ratio are significantly associated with the presence and severity of hypertensive retinopathy.
Answers are grounded in this paper and cite their sources.
Supports lipid assessment in essential hypertension; leaves open causal role and therapeutic impact on retinopathy.
Aim: To study the association of components of lipid profile with hypertensive retinopathy in patients of essential hypertension. Materials and Methods: A Cross Sectional Study was carried out in 80 patients who were diagnosed to have systemic Hypertension. Patients having myopia, having diabetes, hazy ocular media, and other retinal problems were excluded from the study.A detailed examination of patient's hypertensive status was done by physician after ruling out secondary causes of hypertension. Full ophthalmological examination was carried out. All the patients were investigated for fasting serum lipid profile. Results: Out of the 80 patients with essential hypertension, 55 (55%) had retinopathy and the remaining 25 (25%) subjects had no retinopathy were mainly concentrated in the 6th decade (69.70%), increasing thereafter up to 83.78% who were over 60 years of age. This shows the increasing prevalence of hypertensive retinopathy with increasing age.No sex preponderance toward developing retinopathy was found in this study . A positive correlation of hypertensive retinopathy was found with total cholesterol (P < 0.002), low-density lipoprotein (LDL)-cholesterol (P < 0.0001),Serum triglycerides (P < 0.01),and an low-density lipoprotein:high-density lipoprotein (LDL:HDL) ratio (P < 0.002).Conclusion: The duration of hypertension was found to be strongly associated with development of hypertensive retinopathy.This study proved a definite association between serum lipid parameters and prevalence of hypertensive retinopathy.
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Singh et al. (2022) conducted a cross-sectional in Essential hypertension (n=80). Elevated serum lipid parameters vs. Normal serum lipid parameters was evaluated on Association of hypertensive retinopathy with serum LDL-cholesterol levels (p=<0.0001). Elevated serum levels of total cholesterol, LDL-cholesterol, and triglycerides were significantly associated with an increased prevalence and severity of hypertensive retinopathy in patients with essential hypertension.
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