What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Hypertension (n=313). Intervention: Age >50 years vs. Age <50 years. Primary outcome: Hypertensive retinopathy (p=0.0004779).

What does this research mean for the field?

Hypertensive retinopathy occurs in nearly 30% of hypertensive patients and is significantly associated with older age, male sex, and a duration of hypertension exceeding 5 years. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To determine the prevalence of hypertensive retinopathy and identify its associated clinical risk factors among patients with hypertension.

January 1, 2017Journal of Hypertension Open Access

Prevalence and Risk Factors of Hypertensive Retinopathy in Hypertensive Patients

Q: What are the key findings of this study?

Hypertensive retinopathy was present in 29.4% of patients and was significantly more frequent in those aged >50 years compared to <50 years (68.48% vs. 31.52%, P=0.0004779).

Q: What does this research mean for the field?

Hypertensive retinopathy occurs in nearly 30% of hypertensive patients and is significantly associated with older age, male sex, and a duration of hypertension exceeding 5 years. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Q: What question did this study set out to answer?

To determine the prevalence of hypertensive retinopathy and identify its associated clinical risk factors among patients with hypertension.

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Key result

Age over 50 linked to higher hypertensive retinopathy frequency, accounting for ~68% of all cases.

P=0.0004779
n=313

Why the study?

Hypertensive retinopathy is a major complication of hypertension and may indicate other hypertensive complications such as nephropathy, but its prevalence and risk factors need further description.

Population

313 hypertensive patients at Hypertension and Research Center, Rangpur, Bangladesh

Comparison

Patients with hypertensive retinopathy vs without hypertensive retinopathy

Design

Cross-sectional study using systemic sampling

Authors

RMRatindra Nath MondalDinajpur Medical College MMMd. Abdul MatinSungkyunkwan University MRMoni RaniDinajpur Medical College

Discussion

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Implication

May inform risk stratification by age and duration; hypothesis-generating pending prospective validation.

Key Points

To determine the prevalence of hypertensive retinopathy and identify its associated clinical risk factors among patients with hypertension.
Conducted a cross-sectional study using systematic sampling of patients presenting to an outpatient hypertension center in Rangpur, Bangladesh (N=384 sampled; 313 hypertensive patients analyzed).
Evaluated retinopathy grading via ophthalmic examination and assessed associations with age, sex, hypertension duration, and comorbid target organ damage including stroke, IHD, and CKD.
Hypertensive retinopathy occurred in 29.4% (n=92) of patients, with grade 1 retinopathy being the most prevalent (14.7%) and an average latency to onset of 6.73 years.
Retinopathy rates were significantly elevated in patients aged >50 years compared to ≤50 years (68.48% vs. 31.52%, p=0.0004779) and in those with hypertension duration >5 years (34.56% vs. 23.84%, p=0.00000251).
Concomitant target organ damage (IHD, stroke, and CKD) was documented in 21.73% of patients with retinopathy compared to 19.90% of those without retinopathy.

Study Design

Type

Cross-Sectional (n=313)

Multicenter

Structured PICO

Population

313 hypertensive patients evaluated in a cross-sectional study to determine the prevalence and risk factors of hypertensive retinopathy.

Outcome

Prevalence and risk factors of hypertensive retinopathysurrogate

Main Result

Absolute Event Rate: 68.48% vs 31.52%

p-value: p=0.0004779

Nearly one-third of hypertensive patients in this cohort had hypertensive retinopathy, which strongly correlated with older age, male sex, and longer duration of hypertension.

Cite This Study

Mondal et al. (2017) conducted a cross-sectional in Hypertension (n=313). Age >50 years vs. Age <50 years was evaluated on Hypertensive retinopathy (p=0.0004779). Hypertensive retinopathy was present in 29.4% of patients and was significantly more frequent in those aged >50 years compared to <50 years (68.48% vs. 31.52%, P=0.0004779).

synapsesocial.com/papers/6aaf7e498976e698ef3515ce https://doi.org/10.4172/2167-1095.1000241

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Prevalence and Risk Factors of Hypertensive Retinopathy in Hypertensive Patients

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Prevalence and Risk Factors of Hypertensive Retinopathy in Hypertensive Patients

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

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