Key result
Patients with functional abdominal pain had higher basal parasympathetic activity (MSSD 64 vs 46 msec; P=0.03) and a diminished sympathetic heart rate response to stress compared to healthy controls.
Why the study?
Does autonomic nervous system function differ in patients with functional abdominal pain compared to healthy controls and those with organic abdominal pain?
Population
62 participants, comprising 22 patients with functional abdominal pain, 14 healthy controls, and 26 patients…
Comparison
Laboratory stress test (mental arithmetic) vs Healthy controls and patients with organic…
Design
Cross-sectional
Authors
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May support autonomic assessment in functional abdominal pain; leaves open causality and clinical utility.
Observational (n=62)
Does autonomic nervous system function differ in patients with functional abdominal pain compared to healthy controls and those with organic abdominal pain?
Absolute Event Rate: 64% vs 46%
p-value: p=0.03
Patients with functional abdominal pain exhibit increased basal parasympathetic neural activity and a diminished sympathetic neural response to laboratory stress compared to healthy controls.
Jørgensen et al. (1993) conducted an observational in Functional abdominal pain (n=62). Laboratory stress test (mental arithmetic) vs. Healthy controls and organic abdominal pain patients was evaluated on Basal parasympathetic neural activity (mean square successive differences of R-R intervals) (p=0.03). Patients with functional abdominal pain had higher basal parasympathetic activity (MSSD 64 vs 46 msec; P=0.03) and a diminished sympathetic heart rate response to stress compared to healthy controls.
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