Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 5, 2022Journal of Cardiovascular Development and DiseaseOpen Access

Complementary Role of Combined Indirect and Direct Cardiac Sympathetic (Hyper)Activity Assessment in Patients with Heart Failure by Spectral Analysis of Heart Rate Variability and Nuclear Imaging: Possible Application in the Evaluation of Exercise Training Effects

View Full Paper
Ask AI
Bookmark
Share

Key result

Combined HRV and MIBG imaging provides complementary insights on cardiac sympathetic hyperactivity in CHF.

Why the study?

Assessing cardiac autonomic status is clinically important in CHF, but the complementary roles and potential combined use of spectral analysis of HRV and MIBG imaging needed reviewing.

Does the combined use of HRV and MIBG imaging improve the assessment of cardiac sympathetic hyperactivity and the effects of exercise training in patients with chronic heart failure?

Design

Review

Authors

FIFerdinando IellamoUniversity of Rome Tor VergataMPMarco Alfonso PerroneUniversity of Rome Tor VergataACAndrea CiminiSan Salvatore Hospital

Discussion

Loading...

Member takes

Implication

May support complementary sympathetic assessment in HF; leaves open prospective validation for exercise training guidance.

Structured PICO

Does the combined use of HRV and MIBG imaging improve the assessment of cardiac sympathetic hyperactivity and the effects of exercise training in patients with chronic heart failure?

P
Population
Patients with chronic heart failure (CHF) and reduced ejection fraction
I
Intervention
Combined indirect (spectral analysis of heart rate variability) and direct (iodine-123 metaiodobenzylguanidine [MIBG] nuclear imaging) cardiac sympathetic activity assessment
O
Outcome
Detection of cardiac sympathetic hyperactivity and assessment of non-pharmacological treatments (exercise training effects)surrogate

Combined assessment using HRV and MIBG imaging provides complementary presynaptic and postsynaptic information on cardiac sympathetic activity, which may be useful for evaluating exercise training effects in heart failure.

Cite This Study

Iellamo et al. (2022) conducted a review in Chronic heart failure. Heart rate variability (HRV) and MIBG imaging was evaluated. Combined assessment of heart rate variability and MIBG imaging provides complementary information on cardiac sympathetic hyperactivity in chronic heart failure.

synapsesocial.com/papers/6a0e9e2025c30b2cc7f99ca2https://doi.org/10.3390/jcdd9060181

Topics

Heart failureHFrEF treatment
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Increased myocardial [123I]-metaiodobenzylguanidine uptake after enalapril treatment in patients with chronic heart failure.1996 · 67 citations
  2. 2Parasympathetic Nervous System and Heart Failure2008 · 459 citations
  3. 3Prognostic significance of cardiac <sup>123</sup>I metaiodobenzylguanidine imaging for mortality and morbidity in patients with chronic heart failure: a prospective study2001 · 128 citations
  4. 4Mode of Death in Patients with Newly Diagnosed Heart Failure in the General Population2008 · 46 citations