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What are the modalities used for cardiac sympathetic imaging in heart failure?
What are the modalities used for cardiac sympathetic imaging in heart failure?
Cardiac sympathetic imaging with (123)I-MIBG and PET tracers provides a method to investigate autonomic nervous system activity in heart failure.
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Supports autonomic imaging in HF evaluation; leaves open clinical utility of developing PET tracers pending prospective data.
The autonomic nervous system plays an important role in the pathology of heart failure. The single-photon emission computed tomography tracer iodine-123-metaiodobenzylguanidine ((123) I-MIBG) can be used to investigate the activity of the predominant neurotransmitter of the sympathetic nervous system, norepinephrine. Also, positron emission tomography tracers are being developed for the same purpose. With (123) I-MIBG as a starting point, this brief review introduces the modalities used for cardiac sympathetic imaging.
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Christensen et al. (2013) studied this question.
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